Quantitative estimation of ethanol content in eribulin mesylate injection using headspace gas chromatographic with flame ionization detector [HS-GC-FID]
Downloads
Published
DOI:
https://doi.org/10.58414/SCIENTIFICTEMPER.2024.15.2.11Keywords:
Ethanol content, HS-GC, Eribulin mesylate injection, ICH guidelines, Validation.Dimensions Badge
Issue
Section
License
Copyright (c) 2024 The Scientific Temper
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
A specific HS-GC method has been developed, optimized, and validated for the quantitative estimation of ethanol content in eribulin mesylate injection. Chromatographic separation was achieved on DB-624 column (30 m x 0.32 mm, 1.8 μm), consisting of 6% cyanopropyl and 94% polydimethylsiloxane as stationary phase and passing nitrogen carrier gas. The performance of the method was assessed by evaluating the specificity, linearity, precision, and accuracy of experiments. The correlation coefficient value of the linearity experiment was 0.9999. The average recoveries for the accuracy were in the range of 98.7 to 102.4%. The results proved that the method is suitable for the quantitative estimation of ethanol content in eribulin mesylate injection.Abstract
How to Cite
Downloads
Similar Articles
- Getasew Mesfin, Isreal Zewide, Abdeta Jembere, Physicochemical Characterization of Vermicompost and its Effect on Acidic Soils in Ethiopia , The Scientific Temper: Vol. 14 No. 01 (2023): The Scientific Temper
- M. Iniyan, A. Banumathi, Brower blowfish nash secured stochastic neural network based disease diagnosis for medical WBAN in cloud environment , The Scientific Temper: Vol. 15 No. 03 (2024): The Scientific Temper
- Sanjeev Kumar, Saurabh Charaya, Rachna Mehta, Multi-Metric Evaluation Framework for Machine Learning-Based Load Prediction in e-Governance Systems , The Scientific Temper: Vol. 17 No. 01 (2026): The Scientific Temper
- V.K. Pandey, R.N. Mishra, Shipra Upadhyaya, Anand Swaroop, TOXICITY OF PAPER MILL EFFLUENTS EFFECTS LIVER PROTEIN AND AMINO ACID DURING ANNUAL BREEDING CYCLE OF HETEROPNEUSTES FOSSILIS (BLOCH) , The Scientific Temper: Vol. 1 No. 01 (2010): The Scientific Temper
- Annalakshmi D., C. Jayanthi, An asymmetric key encryption and decryption model incorporating optimization techniques for enhanced security and efficiency , The Scientific Temper: Vol. 15 No. 03 (2024): The Scientific Temper
- S. Ranganathan, V. Umadevi, FDBSCAN-MBKSched: A Hybrid Edge-Cloud Clustering and Energy-Aware Federated Learning Framework with Adaptive Update Scheduling for Healthcare IoT , The Scientific Temper: Vol. 16 No. 12 (2025): The Scientific Temper
- Maya Kumari, Vikas Y Patade, Z Ahmad, INVOLVEMENT OF PLANT MICRORNAS IN ABIOTIC STRESS RESPONSES , The Scientific Temper: Vol. 1 No. 01 (2010): The Scientific Temper
- Hariini Chandramohan, Sethu Gunasekaran, Comparative analysis on the photocatalytic activity of titania and silica nanoparticles using dye discoloration and contact angle test , The Scientific Temper: Vol. 16 No. 01 (2025): The Scientific Temper
- Amresh Kumar Singh, Manjit Singh Chhetri, Pushyamitra Mishra, Toughness and Ductile Brittle Transition Temperature of Different Mineral Filler Reinforced TPOs Composites , The Scientific Temper: Vol. 13 No. 02 (2022): The Scientific Temper
- S. Nagarani, Amalraj P., Lakshay Phor, Nishank S. Pimple, Banashree Sen, Ramaprasad Maiti, Vikas S. Jadhav, Innovative technological advancements in solving real quadratic equations: Pioneering the frontier of mathematical innovation , The Scientific Temper: Vol. 15 No. 03 (2024): The Scientific Temper
<< < 1 2 3 4 5 6 7 8 9 10 > >>
You may also start an advanced similarity search for this article.
