Quantitative estimation of ethanol content in eribulin mesylate injection using headspace gas chromatographic with flame ionization detector [HS-GC-FID]
Downloads
Published
DOI:
https://doi.org/10.58414/SCIENTIFICTEMPER.2024.15.2.11Keywords:
Ethanol content, HS-GC, Eribulin mesylate injection, ICH guidelines, Validation.Dimensions Badge
Issue
Section
License
Copyright (c) 2024 The Scientific Temper
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
A specific HS-GC method has been developed, optimized, and validated for the quantitative estimation of ethanol content in eribulin mesylate injection. Chromatographic separation was achieved on DB-624 column (30 m x 0.32 mm, 1.8 μm), consisting of 6% cyanopropyl and 94% polydimethylsiloxane as stationary phase and passing nitrogen carrier gas. The performance of the method was assessed by evaluating the specificity, linearity, precision, and accuracy of experiments. The correlation coefficient value of the linearity experiment was 0.9999. The average recoveries for the accuracy were in the range of 98.7 to 102.4%. The results proved that the method is suitable for the quantitative estimation of ethanol content in eribulin mesylate injection.Abstract
How to Cite
Downloads
Similar Articles
- Syam Sundar. S, Direct reuse of scour and bleach effluent water for cotton knitted fabrics , The Scientific Temper: Vol. 14 No. 02 (2023): The Scientific Temper
- Sowmiya M, Banu Rekha B, Malar E, Assessment of transfer learning models for grading of diabetic retinopathy , The Scientific Temper: Vol. 14 No. 02 (2023): The Scientific Temper
- Neetu Singh, Ravindra Kumar Singh, Diazinon Effect on Behavior and Morphology of Catfish Clarias batrachus (Linnaeus, 1758) , The Scientific Temper: Vol. 13 No. 01 (2022): The Scientific Temper
You may also start an advanced similarity search for this article.
