Features of diagnosing ovarian tumors in women of pre- and postmenopausal age
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https://doi.org/10.58414/SCIENTIFICTEMPER.2023.14.4.06Keywords:
ovarian cancer, pre- and postmenopausal women, tumor-associated marker CA-125, HE-4, screeningDimensions Badge
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Currently, one of the main ways to fight cancer, which can improve the results of treatment of ovarian neoplasms, is screening. Presently, the issue of organizing and conducting preventive examinations of women, including those of reproductive age, is one of the most urgent problems of primary health care institutions. The subjects of the study were 168 pre- and postmenopausal patients aged 20 to 60 years with ovarian tumors suspected of oncological pathology, who received treatment on the basis of the Tashkent city branch of the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology for the period from 2018 to 2022, taking into account the selected age interval. An assessment was made of laboratory research methods, such as: general blood count, biochemical blood test, general urinalysis, tumor-associated marker CA-125, HE-4. In the comparative analysis of risk factors, when ovarian tumors develop in pre- and postmenopausal women, malignant and borderline ovarian tumors have complaints, parity, gynecological anamnesis, and the presence of extragenital diseases, which do not have specific characteristics for malignant or borderline tumors. therefore, it does not provide sufficient information in the process of diagnosing ovarian tumors. The sonographic characteristics associated with the degree of ovarian tumor malignancy were examined, and the tumor had a solid component (p <0.001), the presence of obstructions (p = 0.0005), and the presence of growth on the inner surface of the capsule (p <0.001), the presence of a significant amount of free fluid in the pelvic cavity (p <0.001), the roughness of the surface of the tumor capsule (p < 0.001) were observed to be characteristic of more dangerous processes.Abstract
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